See also entries under syndrome. The corresponding lesion on the glans penis is termed erythroplasia of Queyrat. Brill- Zinsser disease. Acute attacks are sometimes called pseudogout. Calv. The most commonly seen are spongiform degeneration of neurons, neuronal loss, gliosis, and amyloid plaque formation, accompanied by rapidly progressive dementia, myoclonus, motor disturbances, and encephalographic changes, with death occurring usually within a year of onset. Crigler- Najjar disease. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. Conforming with or conformable to justice, law, or morality: do the right thing and confess. In accordance with fact, reason, or truth; correct: the right answer. No other system matches the diversity of colleges and universities accessible through the Common App. Explore and apply to schools across the world. Affiliate marketing is a type of performance-based marketing in which a business rewards one or more affiliates for each visitor or customer brought by the affiliate's own marketing efforts. The industry has four core players. Curiosity makes you smarter. We’re a new type of media company, for the intellectually curious. We cover intriguing topics in visual, short form, mobile friendly experiences. We’re making learning easier and. In the congenital form, there is hepatosplenomegaly with cirrhosis, and microcephaly with mental or motor retardation. Acquired disease may cause a clinical state similar to infectious mononucleosis. When acquired by blood transfusion, postperfusion syndrome results. The adult form is associated with moderate anemia and thrombocytopenia, and yellowish pigmentation of the skin; in the infantile form there is, in addition, marked central nervous system impairment; in the juvenile form there are rapidly progressive systemic manifestations but moderate central nervous system involvement. Having trouble identifying your pills? Reed- Sternberg cells are characteristically present. Four types have been distinguished on the basis of histopathologic criteria. It is often associated with vasculitis of the large coronary vessels. Kienb. Pathologically, there is rapidly progressive cerebral demyelination and large globoid bodies (swollen with accumulated cerebroside) in the white substance. Kufs' disease. See also obstructive small airways d. Disease may be caused by developmental disturbances, genetic factors, metabolic factors, living agents, or physical, chemical, or radiant energy, or the cause may be unknown. Adams- Stokes (Adams- Stokes syndrome),n. Cheyne- Stokes respirations. See also syndrome, general adaptation. Addison's,n. pr a chronic adrenocortical insufficiency caused by bilateral tuberculosis, aplasia, atrophy, or degeneration of the adrenal glands. ![]() ![]() Symptoms include severe weakness, weight loss, low blood pressure, digestive disturbances, hypoglycemia, lowered resistance to infection, and abnormal pigmentation (bronze color of the skin, with associated melanotic pigmentation of the oral mucosa, especially of the gingival tissues). Addison's disease, Cushing's syndrome, adrenogenital syndrome, and primary aldosteronism. See disease, autoimmune. Includes various hemolytic anemias, idiopathic thrombocytopenias, rheumatoid arthritis, systemic lupus erythematosus, glomerulonephritis, scleroderma, Hashimoto's thyroiditis, and Sj. Such a disease often results in lesions of the oral structures, particularly the mucosal surfaces. Brill- Symmers,n. See lymphoblastoma, giant follicular. B. Local lesions occur at the site of injury with a regional adenitis that is out of proportion to the primary lesion occurring within 1 to 3 weeks. Systemic symptoms of infection may occur. Diagnosis is confirmed by serologic tests. See disease, autoimmune. COPD),n a disease marked by decreased expiratory flow rates resulting in increased total lung capacity. Patients with this condition are prone to acute respiratory failure from infections or general anesthesia. These diseases have similar biochemical structural alterations and include rheumatic fever, scleroderma, rheumatoid arthritis, systemic lupus erythematosus, periarteritis, and serum sickness. A disease with the capacity for maintenance by natural modes of spread (e. Cushing's,n. pr hypercortisolism that results from an adrenal or pituitary neoplasm. The term Cushing's syndrome refers to hypercortisolism that is not related to an endogenous process. See disease, salivary gland. ![]() Darier's (keratosis follicularis),n. The oral lesions are whitish papules of the gingiva, tongue, or palate. It is characterized histologically by the presence of corps ronds. Used mainly in reference to avitaminosis. ![]() Often used to mean members of the same generation and occasionally used synonymously with hereditary disease. The secretion of the affected mucous glands is abnormally viscous. B1. 9; spread via the upper respiratory tract, this virus impacts on children more strongly than adults. Also called erythema infectiosum. Gaucher's(g. This glycoprotein accumulates in the reticuloendothelial system and leads to splenomegaly, hepatomegaly, lymph node enlargement, and bone defects. GVHD),n a potentially deadly condition resulting from allogenically transplanted hematopoietic cells that reject host cells in the transplant recipient. In early stages, this condition may result in lichenoid and erosive lesions on the oral mucosa. The human form is characterized by fever, nausea, vomiting, malaise, and ulcerative stomatitis. Skin lesions consisting of vesicles may appear, usually on the palms of the hands and soles of the feet. Spontaneous regression usually occurs within 2 weeks. Hand- Sch. Symptoms include chest pain or discomfort (angina pectoris), ventricular fibrillation, heart attack (myocardial infarction), or sudden death. Also known as coronary artery disease and coronary heart disease. The process most often involves the mitral valve. Thyrotoxicosis is an important cause of auricular fibrillation. C,n a disease resulting from an abnormal hemoglobin (hemoglobin C); occurs primarily in African Americans and causes a mild normochromic anemia, target cells, and vague, intermittent arthralgia. Rh incompatibility or with blood transfusions in which there is an incompatibility of the ABO blood system. Several forms of the disease occur: erythroblastosis fetalis, congenital hemolytic disease, icterus gravis neonatorum, and hydrops fetalis. B . Three main types of mendelian heredity are recognized: dominant, recessive, and sex- linked. See disease, autoimmune. Some infectious diseases involving the oral tissues are herpes zoster, herpetic gingivostomatitis, moniliasis, syphilis, and tuberculosis. Langerhans cell (Langerhans cell histiocytosis),n a group of three diseases identified by an abundance of Langerhans cells–eosinophils combined with histiocytic cells. See also disease, Letterer- Siwe; disease, Hand- Sch. Results in enlargement of the lymph nodes, spleen, and liver, defects of the flat and long bones, anemia, and sometimes purpura. Included are Gaucher's disease, Niemann- Pick disease, and the Hand- Sch. Other storage diseases include lipochondrodystrophy (gargoylism) and cerebral sphingolipidosis. Fatty plaque buildup and thrombosis formation in these vessels may lead to a myocardial infarction, cerebral infarction, and circulation problems in the limbs. It is often a complication of long- term diabetes. These include hyperparathyroidism, osteoporosis, osteomalacia, rickets, and the many diseases associated with an abnormal abundance of Langerhans cells. Mikulicz'(mik. Such changes reveal few structural alterations, and the highly differentiated contents of muscle fibers tend to react as a whole. The pathologic features that distinguish one muscle disease from another are the age and character of changes within a muscle, distribution of those changes within one or several muscles, presence of inflammatory cells and parasites, and coexistence of pathologic changes in other organs. Muscles undergo a number of degenerative changes. There are alterations in the striation in certain pathologic states caused by cloudy swelling, granular degeneration, waxy or hyaline degeneration, and other cellular modifications such as multiplication of the sarcolemmic nuclei and phagocytosis of muscle fibers. Niemann- Pickn. pr a congenital, familial disorder occurring mainly in Jewish female infants that terminates fatally before the third year and is characterized by the accumulation of the phospholipid sphingomyelin in the cells of the reticuloendothelial system. Many oral and paraoral defects are associated with generalized defects (e. Peutz- Jeghers, Franceschetti, Ehlers- Danlos, Pierre Robin, and Sturge- Weber syndromes; hemorrhagic telangiectasia; Crouzon's disease; sickle cell disease; acatalasemia; white spongy nevus; xeroderma pigmentosum; gargoylism; neurofibromatosis; familial amyloidosis; and achondroplasia). Paget's, of bone (osteitis deformans),n. It is represented radiographically by a cotton- wool appearance of the bone and microscopically by a mosaic bone pattern with so- called reversal lines. Hypercementosis and loosening of the teeth may be significant manifestations. Increased serum alkaline phosphatase may be an early finding. Parkinson's,n. pr a progressive neurologic disorder for which there is no known cure that is thought to be the result of neuron degeneration in the section of the brain controlling spontaneous movement and balance. The disease causes postural changes, tremors, muscle rigidity, and weakness. Oral manifestations include difficulty in swallowing and excess salivation. Diseases affecting the periodontium include aggressive and necrotizing types, as well as gingivitis. Etiologic factors may be local or systemic or may involve an interplay between the two. Periodontal diseases may be involved in increasing the risk and course of systemic diseases. Pott's,n. pr a spinal curvature (kyphosis) resulting from tuberculosis. Various conditions may be included (e. See also disorder, psychophysiologic, autonomic, and visceral. Manifestations include jaundice, purpura, hemolytic anemia, vomiting, diarrhea, chronic eczema, and failure to gain weight. S) that permits the formation or results in the formation of sickle- shaped red blood cells. Two forms of the disease occur: sickle cell trait and sickle cell anemia. See also anemia, sickle cell; trait, sickle cell. Simmonds' (pituitary cachexia, hypophyseal cachexia, hypopituitary cachexia),n. Takahara'sn. pr a form of rare progressive oral gangrene occurring in childhood and seen only in Japan. Apparently related to a congenital lack of the enzyme catalase (acatalasemia). Characterized by a mild to severe form of a peculiar type of oral gangrene that may develop at the roots of the teeth or the tonsils. Loss of teeth occurs, with necrosis of the alveolar bone.
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